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ARTESUNATE Excipients

ARTESUNATE Excipients

Product Details:

  • CAS No 88495-63-0
  • Application Pharmaceutical Industry
  • Color White
  • Form Powder
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ARTESUNATE Excipients Price And Quantity

  • 25

ARTESUNATE Excipients Product Specifications

  • Pharmaceutical Industry
  • White
  • 88495-63-0
  • Powder

ARTESUNATE Excipients Trade Information

  • Letter of Credit at Sight (Sight L/C) Telegraphic Transfer (T/T)
  • OFFERED IN EXPORT WORTHY PACKING OF 25 KILOS OR AS PER OUR CUSTOMER REQUIREMENTS
  • Australia North America Eastern Europe Western Europe Africa Central America Middle East South America Asia

Product Description

Artesunate is a water-soluble, semi-synthetic derivative of the sesquiterpine lactone artemisinin with anti-malarial, anti-shistosomiasis, antiviral, and potential anti-neoplastic activities. Upon hydrolysis of artesunate's active endoperoxide bridge moiety by liberated heme in parasite-infected red blood cells, reactive oxygen species and carbon-centered radicals form, which have been shown to damage and kill parasitic organisms. Additionally, in vitro studies demonstrate that this agent induces dna breakage in a dose-dependent manner. Artesunate has also been shown to stimulate cell differentiation, arrest the cell cycle in the g1 and g2m phases, inhibit cell proliferation, and induce apoptosis through mitochondrial and caspase signaling pathways. Artemisinin is isolated from the plant artemisia annua. Artesunate is part of the artemisinin group of drugs that treat malaria. It is a semi-synthetic derivative of artemisinin that is water-soluble and may therefore be given by injection.
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